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KMID : 1025520210630010025
Journal of Animal Science and Technology
2021 Volume.63 No. 1 p.25 ~ p.35
A genome-wide association study (GWAS) for pH value in the meat of Berkshire pigs
Park Jun

Lee Sang-Min
Park Ja-Yeon
Na Chong-Sam
Abstract
The purpose of this study is to estimate the single nucleotide polymorphism (SNP) effect for pH values affecting Berkshire meat quality. A total of 39,603 SNPs from 1,978 heads after quality control and 882 pH values were used estimate SNP effect by single step genomic best linear unbiased prediction (ssGBLUP) method. The average physical distance between adjacent SNP pairs was 61.7kbp and the number and proportion of SNPs whose minor allele frequency was below 10% were 9,573 and 24.2%, respectively. The average of observed heterozygosity and polymorphic information content was 0.32 ¡¾ 0.16 and 0.26 ¡¾ 0.11, respectively and the estimate for average linkage disequilibrium was 0.40. The heritability of pH45m and pH24h were 0.10 and 0.15 respectively. SNPs with an absolute value more than 4 standard deviations from the mean were selected as threshold markers, among the selected SNPs, protein-coding genes of pH45m and pH24h were detected in 6 and 4 SNPs, respectively. The distribution of coding genes were detected at pH45m and were detected at pH24h.
KEYWORD
Berkshire, pH value, Heritability, Linkage disequilibrium, Genome-wide assocition study
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